Antibacterial and fungicidal activities of ethanol extracts of 38 species of plants (2025)

In Vitro Antibacterial Activities of Various Ethanolic Medicinal Plant Extracts Against Some Human Pathogenic Bacteria

Turkish Journal of Agriculture - Food Science and Technology, 2020

The widespread use of antibiotics often causes increase in the bacterial drugs resistance and causes many side effects in humans. Medical plants have antimicrobial effects against most pathogenic bacteria and can serve as harmless replacement to antibiotics. The aim of this study was to assess the antibacterial effect of five medicinal plant prevailed in Kurdistan region namely; Cinnamon (Cinnamomum cassia (L.) D.Don), Nigella (Nigella sativa L.), Allium (Allium hirtifolium Boiss.), Carrot (Daucus carota L.), and Fennel (Foeniculum vulgare Mill.) against pathogenic Gram positive bacteria (Staphylococcus aureus), and pathogenic Gram negative bacteria (Salmonella typhi and Escherichia coli). The evaluation of antibacterial activity for these plant extracts was carried out using agar-well diffusion method. Results showed that minimum inhibitory concentration (MIC) of A. hirtifolium against tested bacterial isolates were (25 mg/mL), the lowest MIC values for S. aureus were (25 mg/mL...

Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs

Asian Pacific journal of tropical medicine, 2013

To evaluate in vitro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential. A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use. The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi (Aspergillus fumigatus), yeast (Candida albicans), gram-negative (Acinetobacter baumannii and Pseudomonas aeruginosa) and gram-positive bacteria (Staphylococcus aureus). The activities were tested at three different concentrations of 1.00, 0.10 and 0.01 mg/mL. The data was analysed using Gene data Screener program. The measured antimicrobial activities indicated that out of the 58 plant extracts, 15 extracts showed anti-fungal activity and 23 extracts exhibited anti-bacterial activity. Eight plant extracts have exhibited both anti-bacterial and anti-fungal activities. For instance, Eucommia ulmoides, Polygonum cu...

Antimicrobial Activity of Ethanol Extract of Four Indigenous Plants From South Eastern Nigeria

The Antimicrobial properties of the ethanolic leaf extract of four indigenous plants, Laportia ovalifolia, Spondias mombin, Ficus exasperata and Ageratum conyzoides, on four bacterial isolates (Stapshylococcus aureus, P aeruginosa, Escherichia coli, and Salmonella taphi),were investigated, The minimum inhibitory concentration (MIC) of these plants for each of the test organisms was evaluated. The antimicrobial activity of the plant extracts was determined by the Well diffusion method. The ethanolic leaf extract of all the plants inhibited the test organisms. The widest spectrum of antimicrobial activity was recorded for the ethanolic leaf extracts of S. monbin against P aeruginosa (17.5±0.7 mm) S. aureus (12.0±1.4 mm), E. coli (11.5±0.7 mm), and S. typhi (9.0±0.7mm). This was followed by the ethanolic leaf extract of F. exasperata which showed zone of inhibition of (10.0±1.4 mm) on E. coli (8.0±0.7 mm) on S. aureus, (6.5.5±0.7 mm) on , P. aeruginosa and (6.0±0.7mm) on S. typhi. The antimicrobial activity of Laportia ovalifolia against the organisms was minimal compared to that of S. mombin and F. exasperata. The ethanolic leaf extract of this plant had a narrow antibacterial spectrum against the tested organisms ranging from 8.0 ±1.4mm against S. aureus to 3.0± 1.4mm against S. typhi. The MIC showed that the extracts exhibited antimicrobial properties at concentrations ranging from 12.5ml-200ml and compared favourably with Ciprofloxacine (the positive control) at a concentration of 200 ml. The results obtained in this investigation were discussed in line with the use of the plants under investigation as medicinal plants.

4. Antibacterial activity of ethanolic leaf.pdf

Antimicrobial compounds from herbal sources have good therapeutic potential. In this study, the antibacterial effects of ethanolic extraction of Cotoneaster nummularioides were evaluated for its effect on four food pathogenic bacteria (two gram-positive bacteria; Bacillus cereus (PTCC 1015), Staphylococcus aureus (PTCC 1431) and two gram-negative bacteria; Salmonella Entrica (PTCC 1709) and Escherichia coli (PTCC 1399). The agar disk diffusion method and micro-broth dilution methods were used to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The extract of C. nummularioides showed strong antibacterial activity against two gram-positive micro-organisms tested with higher sensitivity for Bacillus cereus (inhibition zone was 11 mm for the concentration of400mg/ml). Other concentrations of extract didn’t show strong inhibition zone on bacterial strains. The MIC was 200 mg/ml for two gram-positive bacteria (Bacillus cereus and Staphylococcus aureus)and MBC was >400 mg/ml for all bacterial strains.

Antimicrobial Activity of Ethanolic Extracts From Some Medicinal Plant

Australian journal of basic and applied sciences, 2011

This study was carried out to evaluate the antimicrobial activity of clove (Syzygium aromaticum) and thyme (Thymus vulgaris) ethanolic extracts. Different concentrations of ethanolic extracts were prepared and antimicrobial activity was determined against some bacterial, yeast and mold strains. The antimicrobial activity of examined extracts at different concentrations was determined against different cell population of tested strains and expressed as diameter of inhibition zone. Results showed that all clove and thyme ethanolic extracts were markedly inhibited the growth of all tested strains, however, the inhibition effect was differed with regard to the concentration of ethanolic extract as well as the type of tested microorganism. Generally, clove ethanolic extract had stronger antimicrobial activity rather than that of thyme ethanolic extract. Subsequently, clove and thyme are an extremely strong antimicrobial agent with usefull potential applications in food processing as a natural safe unsted of synthetic antimicrobial agents.

Antibacterial activities of the crude ethanol extracts of medicinal plants against Listeria monocytogenes and some other pathogenic strains

African Journal of …, 2010

Searches for substances with antimicrobial activity are frequent and medicinal plants have been considered interesting by some researchers since they are frequently used in popular medicine as remedies for many infectious diseases. The aim of this study was to verify the antibacterial effect of ethanol extracts of 13 plants (Artemisia Herba Alba, Lavandula officinalis L., Matricaria Chamomilla, Eugenia caryophylata , Cistus salvifolius, Mentha suaveolens subsp. Timija, Thymus serpyllum L., Lippia citriodora, Cinnamomum Zeylanicum, Rosa centifolia, Thymus vulgaris L, Rosmarinus officinalis and Pelargonium graveolens) against Listeria monocytogenes and other pathogenic strains. These plants are used more for their therapeutic effects in the aromatization of the traditionally fermented dairy products. For this purpose, the agar well diffusion method was the antimicrobial susceptibility performed test. The major components of extracts tested were identified by gas chromatography coupled with mass spectrometry (GC/MS) analysis. The obtained results revealed in vitro anti-Listeria monocytogenes activities of all the extracts. Also, the extracts of clove, mint timija, cinnamon, cistus, rose, thyme, wild thyme, artemisia, rosemary, geranium and camomile presented in this order promises inhibitory capacity with MIC value between 0.25 mg/mL for clove extract and 6.75 mg/mL for camomile extract. On the other hand, the antimicrobial activity was mainly a function of their chemical composition, in particular in the nature of their major volatile compounds. This study thus confirmed the possibility of using these plants or some of their components in food systems to prevent the growth of foodborne bacteria and to extend the shelf-life of processed foods.

Antibacterial activity of ethanolic extracts of selected medicinal plants against human pathogens

2011

Helicobacter pylori is one of the most common human infectious bacteria. The infection is highly associated with a number of the most important disease of the upper gastrointestinal tract, including gastritis, duodenitis, peptic ulceration, and gastric cancer. In addition, widespread use of antimicrobial agents has resulted in the development of antibiotic resistance. Metabolites of plants, particularly higher plants, have been suggested as alternative potential sources for antibacterial products due to their safe. This study aimed to evaluate antibacterial activities of crude ethanolic extracts of seventeen Vietnamese medicinal plants toward one reference strain and three clinical isolates of Helicobacter pylori using broth micro-dilution bioassay. The antibacterial activities of these extracts were also compared with those of seven antibiotics, amoxicillin, clarithromycin, erythromycin, levofloxacin, azithromycin, tetracycline, and metronidazole. The extracts of Ampelopsis cantoniensis and Cleistocalyx operculatus showed highest antibacterial activity with MIC (MBC) values of 0.31-0.97 (2.5-5) mg/mL, followed by the extracts of Hedyotis diffusa and Ardisia silvestris with MIC (MBC) values of 1.04-1.94 (7.5-10) mg/mL. The remaining plant extracts exhibited moderate, low and very low or no active to the H. pylori strains. Further studies are needed to determine the active compounds from the extracts that showed high antibacterial activity against H. pylori.

In vitro Antimicrobial Effectiveness of Selected Medicinal Plants Extract against Pathogenic Organisms

International Journal of Current Microbiology and Applied Sciences, 2018

Antibacterial and phytochemical effects of ethanol extracts of Syzygium guineense (Willd.) DC barks and Mangifera indica L seeds

Journal of Advanced Biotechnology and Experimental Therapeutics, 2023

Abstract: Bacterial infectious diseases account for thousands of deaths worldwide. Despite their side effects, synthetic antibiotics are currently utilized to treat bacterial infections. There has been an effort to identify alternative medicines of plant origin. Thus, the current study determined in vitro antibacterial activities of Syzygium guineense barks and seeds of Mangifera indica ethanol extracts, as well as their phytochemical profile. The tested bacteria included Salmonella typhi, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. Plant samples were collected from Morogoro region, Tanzania and transferred to Kenyatta University for preparation and extraction. In vitro antibacterial activities were determined by disk diffusion, MIC, and MBC methods. Selected phytochemicals of ethanol extracts were determined qualitatively. The highest antibacterial effects were observed in M. indica extract against B. subtilis, S. aureus, E. coli and S. typhi with zones of inhibition of 20.00 mm, 18.00 mm, 17.67 mm, and 15.67 mm, respectively. Antibacterial effects observed in S. guineense extract against B. subtilis, S. aureus, S. typhi and E. coli produced zones of inhibition of 15.00 mm, 14.33 mm, 10.67 mm, and 9.33 mm, respectively. The extracts showed better antibacterial effects against Gram positive bacteria than Gram negative bacteria. Qualitative phytochemical analysis of the ethanol extracts revealed alkaloids, quinones, flavonoids, phenolics, saponins, steroids, terpenoids, tannins, and glycosides. This study indicates that the ethanol extracts of the plants could be used to develop alternative remedies for treating bacterial infections. The study also suggests that the plant extracts should be subjected to in vivo studies.

In Vitro Antioxidant, Antibacterial and Mechanisms of Action of Ethanolic Extracts of Five Tunisian Plants against Bacteria

Applied Sciences

Pistacia lentiscus, Rosmarinus officinalis, Erica multiflora, Calicotome villosa, and Phillyrea latifolia were considered important medicinal herbs and were used to treat various ailments. The present study was designed to evaluate the antioxidant and antimicrobial activities of ethanolic extracts (EEs). P. lentiscus and R. officinalis were the richest species in phenolic compounds. Similarly, both species showed the highest values of flavonoids. While the EEs of P. lentiscus, E. multiflora, and C. villosa had higher amounts of tannins. These phenolic compounds were evaluated by two different tests, namely diphenyl picrylhydrazyl (DPPH) and ferric iron-reducing power (FRAP). The IC50 values were found to be significant (p < 0.05) for P. lentiscus and E. multiflora. Similarly, both plants showed the highest ferric-reducing antioxidant power (FRAP). This study has been conducted to evaluate the antibacterial potential of EEs against selected bacteria—Gram-positive bacteria (Staphyl...

Investigation on the bioeffects of ethanol extracts of leaf and stem of Momordica charantia on clinical straing of Escherichia coli and Staphlococcus aureas

2011

The bio-effects of the ethanol extracts from the leaf and stem of Momordica charantia were studied with the view to ascertain the medical usefulness ascribed to the plant by the locals. The plant parts, stem and leaf, revealed remarkable activity against Escherichia coli and Staphlococcus aureus. The leaves extracts showed activity at a concentration as low as 10mg/ml against E. coli and 15mg/ml against S. aureus. The Minimum Inhibitory Concentration (MIC) ranges from 10-15mg/ml while Minimum Bactericidal Concentration (MBC) from 30-45mg/ml. The activity of these extracts compared favourably with those of standard antibiotics, Tetracyclines (0.33mg) and Ampicillin (10µg), used in this study. The phytochemical analysis of the extracts showed the presence of tannins, alkaloids, cardiac glycosides and steroids. The presence of these chemicals in the extracts may have been responsible for the activity possessed by the plant extracts.

Antibacterial and antifungal activity of ethanolic extracts from eleven spice plants

Biologia, 2006

Eleven ethanolic extracts from spices of Melissa officinalis, Mentha piperita, Laurus nobilis, Rhus coriaria, Dianthus coryophyllum, Piper nigrum, Capsicum annum, Juniperus oxycedrus, Erica arborea, Colutea arborescens, and Cuminum cyminum collected from various regions of Turkey and local markets were assayed for the in vitro antibacterial activity against 3 Gram-positive (Bacillus subtilis, Staphylococcus aureus and S. epidermidis) and 2 Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa), using agar dilution methods. In addition, their possible toxicity to Candida albicans and Aspergillus niger was determined, using both agar dilution and disc-diffusion methods. The minimum inhibition concentration (MIC) of the M. piperita, L. nobilis and J. oxycedrus ethanolic extracts was 5 mg/mL for all the microorganisms tested. P. aeruginosa was the most sensitive bacterial strain to P. nigrum and E. arborea extracts among both Gram-positive and Gram-negative bacteria tested...

Effect of aqueous and alcoholic plant extracts on inhibition of some types of microbes and causing spoilage of food

The current study included the preparation of the aqueous and alcoholic leaves extract , Ziziphus (Ziziphus spina-christi) and Eucalyptus plant (Eucalyptus camaldulensis) and assessed its antimicrobial activity against reference strains of bacteria and mold. Through chemical compound detection Ziziphus leaves results showed that the aqueous extract and alcohol contain all effective compounds that have been detected except composite resins in aqueous extract and resins in the alcoholic extract. The Eucalyptus leaves aqueous and alcohol extract contained resins, tannins, phenols. It was tested the effectiveness of the inhibitory plant extract against five isolates of bacteria and five isolates of molds. We used a concentration of 50 and 100 mg/ml of each extract. A similar maximum zone of inhibition through the ethanol extract was obtained against both bacteria and mold as well as increased efficiency as dose dependent .

Antibacterial and antioxidant activities of ethanol extracts from trans Himalayan medicinal plants

Pharmacognosy Journal, 2010

the antibacterial and antioxidant activity of the ethanol extracts from some trans Himalayan medicinal plants being used in 'Amchi system of medicine'. these plants were assessed towards selected bacteria as well as in different antioxidant models. Extracts, at concentration between 8 and 250 µg/ml, showed a significant antibacterial effect expressed as minimum inhibition concentration (Mic) against both gram-negative and gram-positive bacteria. in particular, samples of Podophyllum hexandrum leaf, Verbascum thapsus stem against Bacillus subtilis and Salvia sclarea flower against Pseudomonas aeruginosa (Mic = 8 µg/ml) were highly effective. the antioxidant activity was determined by the 2,2-diphenyl -1 picryl hydrazyl (DPPH) method, Ephedra gerardiana leaf (13.30 + 0.6 µg/ml) and Salvia sclarea flower (14.97 + 2.9 µg/ml) were observed with maximum activity. Conclusion of the study supports the use of these plants in traditional medicine to treat various ailments like stomach complaints, wound infections and intestinal disorders etc.

In Vitro Assessment of Antimicrobial Potential of Ethanolic and Aqueous Extract of Against Some Highly Resistant Pathogens

ANNALS of JINNAH SINDH MEDICAL UNIVERSITY, 2020

Objective: To find out the antibacterial potential of ethanolic and aqueous roots extract of Phlomis umbrosa L. against both Gram positive and Gram negative isolates Methodology: Disk diffusion method according to Clinical Laboratory and Standards Institute (CLSI) standard was used to examine the in vitro antibacterial activity of P. umbrosa extract while minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined using broth dilution technique. Miles and Misra technique was also utilized to count the number of colonies CFU/mL of bacteria at different concentrations of extract. Results: All the studied strains showed a diverse range of vulnerability against both ethanolic and aqueous plant extract. Among all tested isolates, ethanolic extract of P. umbrosa showed highly significant activity against Gram positive isolates i.e. S. aureus (20.1 mm) and B. subtilis (22.9 mm) with least MIC (12.5 mg/mL) and MBC (12.5 mg/mL) as compared to Gram negative isolates. A progressive decline in bacterial colonies (CFU/mL) was observed in Miles and Misra technique. One way ANOVA followed by postHoc Tukey test showed the significant differences in antimicrobial activities of plant extract with two tested antibiotics i.e. Amoxicillin and Erythromycin (10 µg/disc) as positive control at p-value of 0.05. The antimicrobial activity of this plant exhibit may be due to the presence of such chemical constituents namely monoterpenoids and sesquiterpenoids compounds. Conclusion: It is concluded that roots ethanolic extract of P. umbrosa has a promising antibacterial potential so it can also be used as an alternative medicine to treat different infections for reducing bacterial resistance and side effects associated with antibiotics.

ANTIBACTERIAL EFFECT OF CRUDE ALCOHOLIC AND AQUEOUS EXTRACTS OF SIX MEDICINAL PLANTS AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI

Antibacterial activity of twelve crude alcoholic and aqueous extracts from six medicinal plants against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 was studied. The medicinal plants included Alstonia macrophylla Wall., Bixa orellana L., Blumea balsamifera (L.) D.C., Azadirachta indica A. Juss., Arcangelisia flava (L.) Merr., and Leea rubra Blume. Crude ethanolic extracts from leaves of Bixa orellana L. and bark of Alstonia macrophylla Wall. showed potential antibacterial effect against S. aureus with minimal inhibitory concentration (MIC) of 62.5 μg/ml. However, none of the crude aqueous and ethanolic extracts showed antibacterial effect against E. coli.

Efficacy of Aqueous and Ethanol Extracts of Some Palestinian Medicinal Plants for Potential Antibacterial Activity

IUG Journal of Natural Studies, 2015

Nine medicinal plants growing in Palestine were screened in vitro for potential antibacterial activity against 6 bacterial strains by well diffusion and micro-dilution techniques. Both aqueous and organic solvents were used. The dried extracts of Sacropoterium spinosum (Rosaceae) (seed), Ruta chalepensis L (Rutaceae) (leaf), Cassia senna (Ligumenosa) (leaf), Lawsonia inermis (Lythraceae) (leaf), Psidium guajava (Myrtaceae) (Leaf), Carataegus azerullus (Rosaceae) (Leaf), Ranunclus asiaticus(Ranunculaceae) (Flowers), Calendula officinalis (Composita) (Flowers),and Salvia syriaca (Labiatae) (leaf) were screened. The bacterial strains tested were; Methicillin-resistant Staphylococcus aureus (MRSA); three strains (1, 2 & 3), multidrug resistant Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella pneumonia. The average diameter of inhibition zones ranged from 9 to 30 mm and 11 to 28 mm for aqueous and ethanol extract, respectively. Methicillin-resistant Staphylococcus aureus (MRSA) was the most inhibited microorganism. Sacropoterium spinosum extract was the most active against Methicillinresistant Staphylococcus aureus (MRSA) and multidrug resistant Pseudomonas aeruginosa. The MIC value of ethanol extract was 0.781 mg/ml against MRSA while 0.390 mg/ml against Pseudomonas aeruginosa. The combination effect of ethanol extracts of (Sacropoterium spinosum with Lawsonia Inermis) on bacterial species tested exhibited a higher effect than that of any individual extract. Such results lead to an interesting promise for further investigation to design potentially active antibacterial augmentative agents of natural sources.

Antimicrobial, phytochemical and traditional studies of selected medicinal plant in Bajaur agency, Pakistan

International Journal of Research in Pharmacy and Science, 2018

Phytochemicals are mainly divided into groups like secondary and primary constituents on the basis of their metabolic function in plants. Primary constituents contain amino acid, proteins chlorophyll, and common sugars whereas secondary constituents contain saponins, alkaloids, terpenoids, phenolic compounds, flavonoids, tannins.The subsequent method was used for the determination of antimicrobial activity. Oxalis corniculata ethanolic extract were 17.5±2.5, 19 ± 0.5 and 15 ± 0.1 against the fungus, (C. albican) Gram positive bacterium (S. aureus) and negative bacterium (E. coli), respectively. Rumex dentatus extract in the same solvent made the 22±0.2, 18± 0.1 and 18±0.1 mm zones of inhibition against the fungus (C. albicans) Gram positive bacterium (S. aureus) and negative bacterium (E. coli), respectively. In addition to this, the extract Tagetes minuta made the 22±0.2, 20±0.2 and 18±0.2 mm zones of inhibition against the fungus (C. albicans) Gram positive bacterium (B. subtilis) and negative bacterium (E. coli), respectively. In other words, the order of inhibitory potential was Cichorium intybus > Medicago sativa > Tagetes minuta > Rumex dentatus >Oxalis corniculata. Ethanolic extract was more effective followed by methanolic, ethyl acetate, hexane and aqueous extracts. Ethanol was more effective followed by methanol, ethyl acetate, hexane and aqueous extracts. Gram positive bacteria were more resistant followed by Gram negative bacteria and fungi

Antibacterial activity of medicinal plants

The antibacterial activity of ethanol extracts of 15 plant species used in the traditional medicine in Jordan and other Middle East countries were tested. Extracts of certain parts of these plants were tested in vitro against 14 pathogenic bacterial species and strains using the agar diffusion method. Results evaluated as the diameter of inhibition zone of bacterial growth showed that 25 mg/well of 12 plant extracts have antibacterial activity on one or more of the tested bacteria. Three plants exhibited broad spectrum antibacterial activity: Punica granatum L., Quercus infectoria Olive., and Rhus coriaria L. The most susceptible bacteria were Pseudomonas aeruginosa, Bacillus cereus and Streptococcus pyogenes (ATCC 12351), and the most resistant species were Escherichia coli (ATCC 25922 and clinical isolates), Klebsiella pneumoniae, Shigella dysentriae (ATCC 49345), and Yersinia enterocolitica (ATCC 9610). The minimum inhibitory concentrations (MIC) of active extracts ranged from 4–...

Antimicrobial and antioxidant activities of alcoholic extracts of Rumex dentatus L

This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues. Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: http://www.elsevier.com/copyright a b s t r a c t In-vitro antimicrobial and antioxidant activities of various concentrations ranging from 150 to 500 mg/ml of alcoholic (methanol and ethanol) extracts of Rumex dentatus were analyzed on different clinical bacterial strains (Shigella flexneri, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus) and fungal strains (Aspergillus versicolor, Aspergillus flavus, Acremonium spp., Penicillium dimorphosporum, Candida albicans, Candida kruesie, Candida parapsilosis) using agar disk diffusion method and broth dilution method (MIC and MBC determination) for antimi-crobial activity and DPPH (1,1-diphenyl-2-picrylhydrazyl) assay, Riboflavin photo-oxidation assay, deoxyribose assay, lipid peroxidation assay for antioxidant activity. The extracts showed maximum inhibitory effect against K. pneumonia and P. aeruginosa with no activity against S. typhimurium from among the bacterial strains while as in case of the fungal strains the maximum effect was observed against C. albicans by both the extracts. MIC and MBC values determined for active fractions of the extracts against some bacterial strains (S. flexneri, K. pneumonia and E. coli) revealed that the test organisms were inhibited by all the extracts with methanol showing lower values of both MIC and MBC indicating it as a better antimicrobial agent. The antioxidant activity showed that the extracts exhibited scavenging effect in concentration-dependent manner on superoxide anion radicals and hydroxyl radicals leading to the conclusion that the plant has got a broad spectrum antimicrobial and antioxidant activity and could be a potential alternative for treating various diseases.